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Italy Cruises from the UK

Set sail from the UK to discover Italy's iconic cities, charming towns and breathtaking coastline on a unforgettable cruise holiday.

Italy (77)
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Western Mediterranean from Southampton, England with the Borealis

Fred Olsen Cruise Lines

Western Mediterranean from Southampton, England with the Borealis

17 nights

From Southampton, England to Southampton, England

Borealis

05/05/2026 - 22/05/2026

Cruise

Full board

Inside

from £2,618 pp

£2,909

Outside

from £3,006 pp

£3,303

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Southampton To Istanbul With Barcelona, Florence/Pisa & Rome

Cruise1st Package

Southampton To Istanbul With Barcelona, Florence/Pisa & Rome

14 nights

From Southampton, England to Istanbul

Sky Princess

13/09/2025 - 27/09/2025

Cruise

Inside

from £1,699 pp

Outside

from £2,099 pp

Italy Cruises from the UK

Italy Cruises from the UK provide a seamless way to explore Italy’s stunning coastlines, historic cities, and world-class cuisine. Set sail directly from the UK and enjoy a relaxing voyage to this iconic Mediterranean destination. Discover even more ways to cruise to Italy below:

Still not what you’re looking for? Explore all Italy Cruises for perfect combination of relaxation, culture and breathtaking scenery, making them a must for travel lovers.

Insider Tip: Many Italian cruise ports provide easy access to historic cities. From Naples, you can explore the ruins of Pompeii, while Venice offers a romantic gondola ride through its iconic canals.

Did you know: Italy is one of the world’s most visited cruise destinations, attracting millions of travellers each year to its stunning coastal towns and historic landmarks.

Looking to book your Italy cruise? Contact our cruise specialists today to find the best deals and create your perfect itinerary.