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Mediterranean Cruises from UK

Head off from a port in the UK to the Mediterranean for a cruise to remember on one of the many offerings available on Cruise1st.

Popular Filters

Departure Dates

Trip Duration

Cabin Category

Price

£

£

Trip price per person based on 2 persons trip

Destination

165

9

144

59

3

1277

3

431

7

26

Cruise lines

3

4

3

29

12

1

38

14

Ships

5

7

8

Themes

7

12

16

77

2

165

114

13

1

80

165 cruises

Luxury No Fly Western Mediterranean

Cunard

Cruise Only

From / To Southampton, England

Queen Anne

Full board

6 Sep 2026

14 nights

No Alternative Dates

Inside

from

£1,355

pp

£1,397

Outside

from

£2,681

pp

£2,708

Balcony

from

£2,860

pp

£3,763

Suite

from

£4,384

pp

£5,768

Best Price Guarantee

Learn more

Western Mediterranean from Liverpool, England with the Bolette

Fred Olsen Cruise Lines

Cruise Only

From / To Liverpool

Bolette

Full board

22 Sep 2026

16 nights

No Alternative Dates

Outside

from

£4,115

pp

£4,199

No Fly Central Mediterranean

P&O Cruises

Cruise Only

From / To Southampton, England

Aurora

Adults Only

4 Oct 2028

19 nights

No Alternative Dates

Inside

from

£2,075

pp

£2,117

Outside

from

£2,387

pp

£2,436

Balcony

from

£3,216

pp

£3,315

Suite

from

£5,556

pp

£5,728

Western Mediterranean from Liverpool, England with the Borealis

Fred Olsen Cruise Lines

Cruise Only

From / To Liverpool

Borealis

Full board

3 Jun 2027

17 nights

No Alternative Dates

Inside

from

£2,351

pp

£2,399

Outside

from

£2,821

pp

£2,879

Balcony

from

£3,958

pp

£4,039

Suite

from

£4,997

pp

£5,099

No Fly Eastern Mediterranean

P&O Cruises

Cruise Only

From / To Southampton, England

Arcadia

Adults Only

10 May 2028

19 nights

Inside

from

£1,685

pp

£1,737

Outside

from

£2,027

pp

£2,068

Balcony

from

£2,924

pp

£3,014

Suite

from

£5,342

pp

£5,507

Mediterranean from Southampton, England with the Arcadia

P&O Cruises

Cruise Only

From / To Southampton, England

Arcadia

Adults Only

20 Nov 2027

19 nights

No Alternative Dates

Inside

from

£1,364

pp

£1,795

Outside

from

£1,461

pp

£2,087

Balcony

from

£2,144

pp

£3,063

Suite

from

£3,899

pp

£4,999

Western Mediterranean from Southampton, England with the Regal Princess

Princess Cruises

Cruise Only

From / To Southampton, England

Regal Princess

30 Apr 2027

15 nights

No Alternative Dates

Inside

from

£1,637

pp

£1,799

Balcony

from

£2,469

pp

£2,599

Suite

from

£3,368

pp

£3,583

Mediterranean from Liverpool, England with the Bolette

Fred Olsen Cruise Lines

Cruise Only

From / To Liverpool

Bolette

Full board

29 Oct 2026

23 nights

No Alternative Dates

Outside

from

£3,625

pp

£3,699

Suite

from

£6,349

pp

£6,479

Western Mediterranean from Southampton, England with the Celebrity Apex

Celebrity Cruises

Cruise Only

From / To Southampton, England

Celebrity Apex

from £49 – £73 off when you book online

11 Sep 2027

14 nights

No Alternative Dates

Inside

from

£2,463

pp

£2,539

Outside

from

£3,552

pp

£3,662

Balcony

from

£3,672

pp

£3,786

Mediterranean from Southampton, England with the Queen Anne

Cunard

Cruise Only

From / To Southampton, England

Queen Anne

Full board

20 Sep 2026

19 nights

No Alternative Dates

Inside

from

£2,444

pp

£2,842

Outside

from

£3,622

pp

£3,980

Balcony

from

£3,236

pp

£4,203

Suite

from

£7,305

pp

£9,131

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Here are some alternatives to help refine your search if the preference is to not fly to your departure:

If you are exploring whether to spend a shorter or longer cruise, then consider different alternatives on offer:

Mediterranean Cruises from UK

Get in touch with our cruise expert

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