The western Mediterranean, the broader Med and beyond — all reachable from Southampton without a single flight. At Cruise1st, one of the UK's leading cruise specialists, our experts help you match the right ship, the right cabin grade and the right fare inclusions to your trip, then put the whole holiday on one booking. Whether you want a fortnight in the sun or a longer voyage that ventures toward North Africa or across the Atlantic, we can add hotels, transfers and insurance so nothing is left to chance.
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87 cruises
No Fly Eastern Mediterranean Discovery


Cruise Only
Up £350 On-Board Spending Money!
From / To Southampton, England
Arcadia
Adults Only
20 Nov 2027
19 nights
No Alternative Dates
Best Price Guarantee
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No Fly Eastern Mediterranean


Cruise Only
Up £350 On-Board Spending Money!
From / To Southampton, England
Arcadia
Adults Only
10 May 2028
19 nights
No Alternative Dates
Mediterranean from Southampton, England with the Arcadia


Cruise Only
New Winter 2028/29 Collection - Get 10% Discount!
From / To Southampton, England
Arcadia
Adults Only
21 Nov 2028
19 nights
No Alternative Dates
No Fly Central Mediterranean


Cruise Only
New Winter 2028/29 Collection - Get 10% Discount!
From / To Southampton, England
Aurora
Adults Only
4 Oct 2028
19 nights
No Alternative Dates
Western Mediterranean from Southampton, England with the Regal Princess


Cruise Only
Save up to £600 per room!
From / To Southampton, England
Regal Princess
30 Apr 2027
15 nights
No Alternative Dates
No Fly Eastern Mediterranean Discovery


Cruise Only
Up £350 On-Board Spending Money!
From / To Southampton, England
Britannia
4 Jun 2027
21 nights
No Alternative Dates
Western Mediterranean from Southampton, England with the Celebrity Apex


Cruise Only
Up to 75% off 2nd guest + up to $700 onboard spend!
From / To Southampton, England
Celebrity Apex
Full board
from £59 – £110 off when you book online
11 Sep 2027
14 nights
No Alternative Dates
No Fly Central Mediterranean Discovery


Cruise Only
Arcadia Farewell Season 2029
From / To Southampton, England
Arcadia
Adults Only
30 Jul 2029
22 nights
No Alternative Dates
Luxury No Fly Western Mediterranean


Cruise Only
Save up to £600 per room!
From / To Southampton, England
Sky Princess
7 Aug 2027
14 nights
Mediterranean from Southampton, England with the Britannia


Cruise Only
From / To Southampton, England
Britannia
2 Jun 2028
21 nights
No Alternative Dates
Every sailing here departs from Southampton, which means most of Britain can reach the port by road or rail with no airport queues at either end. Drive down the morning of departure, arrive by train, or let us arrange a transfer — and you are aboard before the afternoon is out. For a round-trip sailing you come home the same way, with the Med done and dusted and no domestic flight to book. For a one-way itinerary ending in, say, Barcelona or Rome (Civitavecchia), you will need a flight back, and we can book that alongside your cruise so it is all one joined-up holiday.
Sailings run from short breaks of 5 nights through to extended voyages of up to 82 nights, with a median around 16 nights — long enough to take in a real spread of ports. The majority of itineraries are round trips returning to Southampton, though a healthy share are one-way crossings, so it is worth checking the disembarkation port when you browse. Some sailings end in Piraeus (Athens), Alicante or Fort Lauderdale (Port Everglades) — the last is a useful pointer that some voyages cross the Atlantic on the way out or the way back.
The western Mediterranean is where the greatest concentration of sailings is focused, taking in ports along the coasts of southern Europe and the French Riviera. A large number of itineraries are simply labelled Mediterranean, covering a broader sweep that can reach eastward toward Istanbul and Piraeus (Athens), or westward to Marseille and Trieste.
Beyond the Mediterranean itself, a smaller number of sailings venture to North Africa, adding a distinctly different flavour to an otherwise European itinerary. The Canary Islands feature on some departures — a popular winter sun option for those who want warmth without flying. And for the longer voyages, transatlantic crossings use Southampton as the start or end point, often repositioning between Europe and Florida across the seasons.
If you are drawn to Norwegian waters rather than the Med, our Norway cruises from the UK page covers fjord sailings separately.
P&O Cruises leads the way by volume — the natural choice for a no-fuss, quintessentially British sailing straight from home. Cunard Line brings its signature White Star Service and tiered dining to the Mediterranean, with the formality and occasion that regular Cunard guests come back for. MSC Cruises offers a continental feel and a wide variety of itineraries. Princess Cruises and Celebrity Cruises round out the choice for those who want a more contemporary, amenity-rich experience. Fred Olsen Cruise Lines also sails from Southampton, favouring smaller ships and a loyal, experienced clientele.
For a broader look at all cruises available, or to explore all cruises from Southampton across every destination, those pages are a good starting point.
Arcadia accounts for a significant share of P&O’s Mediterranean sailings from Southampton. She is an adults-only ship with a three-tier theatre called The Palladium, a hydro-therapy pool, and Marco Pierre White’s Ocean Grill restaurant — proper dining, not a buffet afterthought. Cabin grades range from a compact interior to a full suite with butler service. See the Arcadia cabins and deck plans for the full layout.
Named by Queen Elizabeth II in 2015, Britannia sails year-round from Southampton. Thirteen restaurants and cafés carry menus from Marco Pierre White, Atul Kochhar and James Martin, and the Headliners Theatre uses LED immersive technology for its productions. The Limelight Club adds a cabaret dimension that feels genuinely different from a standard at-sea evening. Check the Britannia cabins and deck plans if you want to compare grades before you book.
A mid-sized, classic ship with a distinctly British character, Aurora is well suited to longer Mediterranean voyages where space and a relaxed pace matter as much as the ports. She sails directly from Southampton, so there is no preamble. Browse the Aurora cabins and deck plans for grade details.
P&O’s newest large ship, Arvia brings a sun-focused design to Mediterranean sailings from Southampton. See the Arvia cabins and deck plans for the full breakdown.
Art deco design runs throughout Queen Elizabeth — glittering chandeliers, sweeping staircases and a grand lobby that evokes the golden age of ocean travel. The Royal Court Theatre stages West End-calibre shows; Gala evenings fill the Queens Room with live orchestral dancing. Dining is tiered across Britannia, Princess Grill and Queen’s Grill, with Cunard’s famous white-gloved afternoon tea served daily. The Queen Elizabeth cabins and deck plans show how the grades stack up.
The Royal Court Theatre aboard Queen Victoria is the first at sea to feature private boxes — West End-calibre productions every evening. The largest ballroom at sea hosts Cunard’s famous Gala evenings with a live orchestra, and the tiered dining across Britannia, Princess Grill and Queen’s Grill is the most traditional class-dining experience afloat. The Queen Victoria cabins and deck plans cover all grades and deck positions.
MSC’s contribution to these routes comes from two large, well-appointed ships. See the MSC Meraviglia cabins and deck plans and the MSC Virtuosa cabins and deck plans for the full grade breakdown.
Princess’s Southampton Mediterranean programme centres on Sky Princess. The Sky Princess cabins and deck plans are worth a look if you are comparing Princess fare tiers — the Plus package bundles casual dining, Wi-Fi and pre-paid crew appreciation, while the Standard fare lets you pick extras individually.
Fare inclusions vary by cruise line, and it pays to know what you are comparing. On Cunard sailings, the main fare tier gives you flexibility: your choice of stateroom number, priority for upgrades, a low 15% deposit, the ability to amend up to the balance due date, and complimentary shuttle buses at ports. A Saver fare offers the sharpest price in exchange for a pre-allocated stateroom and full payment upfront — worth considering if your dates are fixed. On Princess, the Plus package adds casual dining, a drinks allowance, Wi-Fi, pre-paid gratuities, photos and reserved theatre seating in one price. The Standard fare strips those back so you can choose what to add. Celebrity’s all-inclusive fare bundles a classic drinks package and basic Wi-Fi; the Retreat level steps up to premium drinks, premium Wi-Fi and suite-exclusive lounges. Our team can walk you through every tier so you are not paying for inclusions you do not want — or missing ones you would use every day.
Yes — all-inclusive sailings depart from Southampton to the Mediterranean, covering drinks, meals and gratuities in a single fare. The mix of lines and itineraries that offer this changes with the season, so it is worth calling our team to check which sailings currently carry an all-inclusive tier. If a package deal suits you better — cruise plus flights, hotel nights and transfers in one booking — ask about Cruise1st Packages, which bundle all of that on a single invoice.
Prices start at £342 pp* and reduced fares are available across a range of sailings — up to 26% off the price previously listed for that cabin grade on select departures, though that maximum applies to a single sailing; most discounted departures sit closer to 5% off. Cunard’s Saver fare is a reliable route to a lower price if you are happy to accept a pre-allocated stateroom. Princess’s last-minute and tactical fares can also deliver solid value. Fare types such as early-saver offers and late availability deals appear across lines throughout the year — our team tracks them and can alert you when something matches your dates.
A cruise from Southampton is the easiest kind to book — no flight out, no airport either end for a round trip. But if your itinerary ends abroad, or you want to make a longer break of it with a night in port beforehand, Cruise1st can add the flight home, the hotel the night before, tours ashore and transfers between them. Everything goes on one booking, which means one point of contact if anything changes. We are ABTA and ATOL protected, and rated 4.5/5 on Trustpilot from over 7,000 reviews — so you are covered the whole way.
For something shorter before you commit to a longer Med sailing, our Christmas mini cruises from Southampton and 2-night Southampton departures give you a taste of the ship first. Or browse all 2027 sailings from Southampton if your dates extend into next year. For longer ambitions, world cruises from Southampton and the iconic Queen Mary 2 transatlantic to New York both sail from the same port.
Want to plan by duration? Our 7-day Mediterranean cruise and 14-day Mediterranean cruise from Southampton pages narrow the search by length. For a broader look at the destination, Mediterranean cruises in 2027 covers all UK departure options across that year. Or browse all cruises from the UK if you are open on the port.
*Prices are per person based on 2 people sharing, and are subject to change. This price is not kept up to date and therefore does not reflect live pricing and availability. Prices and any discounts shown were checked on 14 October 2026.
Where a discount is shown, it is a reduction from the price previously listed for that cabin grade on that sailing, not a comparison between cabin grades or against a brochure rate. Discounts and prices shown are not kept up to date: the reduction available now may be smaller, or may have ended, and prices may have changed.
Are There All-Inclusive Mediterranean Cruises Departing from Southampton?
Do I Need a Flight to Join a Mediterranean Cruise from Southampton?
How Long Are Mediterranean Cruises from Southampton?
What Is the Difference Between a Cunard Saver Fare and the Standard Cunard Fare?
Mediterranean Cruises from Southampton