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Mediterranean Cruise from Southampton

Head off from Southampton to the Mediterranean for a cruise to remember on one of the many offerings available on Cruise1st.

Popular Filters

Departure Dates

Trip Duration

Cabin Category

Price

£

£

Trip price per person based on 2 persons trip

Destination

116

9

120

52

3

963

3

318

7

25

Cruise lines

2

3

28

13

1

38

15

Ships

5

8

8

Themes

3

13

12

70

2

116

700

6

43

4

4

11

8

1

81

116 cruises

Luxury No Fly Western Mediterranean

Cunard

Cruise Only

From / To Southampton, England

Queen Anne

Full board

New Ship

Premium Cruise Line

6 Sep 2026

14 nights

No Alternative Dates

Inside

from

£1,484

pp

£1,499

Outside

from

£2,622

pp

£2,648

Balcony

from

£2,681

pp

£3,776

Suite

from

£5,404

pp

£5,749

Best Price Guarantee

Learn more

No Fly Central Mediterranean

P&O Cruises

Cruise Only

From / To Southampton, England

Aurora

Adults Only

Family Friendly

Peninsular Club discount

4 Oct 2028

19 nights

No Alternative Dates

Inside

from

£2,075

pp

£2,117

Outside

from

£2,387

pp

£2,436

Balcony

from

£3,216

pp

£3,315

Suite

from

£5,556

pp

£5,728

No Fly Eastern Mediterranean

P&O Cruises

Cruise Only

From / To Southampton, England

Arcadia

Adults Only

Family Friendly

Peninsular Club discount

10 May 2028

19 nights

Inside

from

£1,685

pp

£1,719

Outside

from

£2,027

pp

£2,068

Balcony

from

£2,924

pp

£3,014

Suite

from

£5,342

pp

£5,507

Mediterranean from Southampton, England with the Arcadia

P&O Cruises

Cruise Only

From / To Southampton, England

Arcadia

Adults Only

Family Friendly

Peninsular Club discount

20 Nov 2027

19 nights

No Alternative Dates

Inside

from

£1,364

pp

£1,795

Outside

from

£1,461

pp

£2,087

Balcony

from

£2,144

pp

£3,063

Suite

from

£3,899

pp

£4,999

Western Mediterranean from Southampton, England with the Regal Princess

Princess Cruises

Cruise Only

From / To Southampton, England

Regal Princess

Family Friendly

Movies under the stars®

Premium Cruise Line

30 Apr 2027

15 nights

No Alternative Dates

Inside

from

£1,637

pp

£1,799

Balcony

from

£2,481

pp

£2,612

Suite

from

£3,368

pp

£3,583

Western Mediterranean from Southampton, England with the Celebrity Apex

Celebrity Cruises

Cruise Only

From / To Southampton, England

Celebrity Apex

Family Friendly

Premium Cruise Line

from £48 – £608 off when you book online

11 Sep 2027

14 nights

No Alternative Dates

Inside

from

£2,380

pp

£2,454

Outside

from

£3,390

pp

£3,495

Balcony

from

£3,529

pp

£3,638

The Retreat

from

£30,420

pp

£31,688

Western Mediterranean from Southampton, England with the Arvia

P&O Cruises

Cruise Only

From / To Southampton, England

Arvia

Family Friendly

New Ship

Peninsular Club discount

5 Jul 2026

14 nights

Inside

from

£1,169

pp

£1,244

Outside

from

£1,364

pp

£1,868

Balcony

from

£1,559

pp

£1,591

Luxury No Fly Western Mediterranean

Princess Cruises

Cruise Only

From / To Southampton, England

Sky Princess

Family Friendly

Movies under the stars®

Premium Cruise Line

28 Aug 2027

14 nights

Inside

from

£1,201

pp

£1,334

Outside

from

£1,609

pp

£1,768

Balcony

from

£1,454

pp

£1,671

Suite

from

£1,917

pp

£2,018

Western Mediterranean from Southampton, England with the Ventura

P&O Cruises

Cruise Only

From / To Southampton, England

Ventura

Family Friendly

Peninsular Club discount

2 Sep 2028

14 nights

No Alternative Dates

Inside

from

£1,149

pp

£1,172

Outside

from

£1,266

pp

£1,292

Balcony

from

£1,461

pp

£1,491

Suite

from

£3,021

pp

£3,114

Western Mediterranean from Southampton, England with the Ventura

P&O Cruises

Cruise Only

From / To Southampton, England

Ventura

Family Friendly

Peninsular Club discount

30 Sep 2028

14 nights

No Alternative Dates

Inside

from

£1,149

pp

£1,172

Outside

from

£1,266

pp

£1,292

Balcony

from

£1,510

pp

£1,541

Suite

from

£2,972

pp

£3,064

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Here are some alternatives to help refine your search if the preference is to not fly to your departure:

If you are exploring whether to spend a shorter or longer cruise, then consider different alternatives on offer:

Mediterranean Cruise from Southampton

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