A 7-night Mediterranean cruise gives you a full week at sea with ports to explore and evenings on board — and Cruise1st, one of the UK's leading cruise specialists, makes booking it straightforward. Every sailing we sell comes with expert advice from people who know these ships and routes well. Because all Mediterranean departures fly from the UK, our team can put together a Cruise1st Package covering your flights, hotel either side and transfers in one booking, so there is nothing left to chase. ABTA and ATOL protected, and rated 4.5/5 on Trustpilot by over 7,000 customers.
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Greek Island Glow with Cruise1st TV's Derek Marks


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Piraeus (Athens), Greece
Scarlet Lady
Adults Only
7 Aug 2027
8 nights
No Alternative Dates
Best Price Guarantee
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Odyssey of Greece & Turkey


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Rome
Odyssey of the Seas
30 Jul 2027
9 nights
No Alternative Dates
Western Mediterranean from Barcelona, Spain with the MSC World Europa


Cruise Only
Save up to 30% OFF!
From / To Barcelona
MSC World Europa
Full board
Tips
up to £44 off when you book online
1 May 2027
7 nights
The Italian Riviera, Sicily & Malta With Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
MSC World Asia
Tips
10 Mar 2027
9 nights
No Alternative Dates
Legends of the Western Med Cruise


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
Legend of the Seas
23 Oct 2027
8 nights
No Alternative Dates
Western Mediterranean from Barcelona, Spain with the MSC Seaview


Cruise Only
Save up to 30% OFF!
From / To Barcelona
MSC Seaview
Full board
Tips
up to £40 off when you book online
4 Apr 2027
7 nights
Luxury Aegean Dreams & Italian Delights


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From Rome To Piraeus (Athens), Greece
Sun Princess
16 Apr 2027
9 nights
No Alternative Dates
Western Mediterranean from Barcelona, Spain with the MSC World Asia


Cruise Only
Save up to 30% OFF!
From / To Barcelona
MSC World Asia
Full board
Tips
up to £55 off when you book online
16 Apr 2027
7 nights
Santorini, Mykonos & Rome With Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Rome
MSC Divina
Full board
Tips
5 May 2027
9 nights
Legends of the Western Mediterranean With Barcelona Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
Legend of the Seas
17 Sep 2027
9 nights
No Alternative Dates
The Mediterranean is the most popular cruise region for British holidaymakers, and a 7-night itinerary fits it well — long enough to take in several ports, short enough to feel manageable. The Western Mediterranean is where the majority of sailings are concentrated, with itineraries departing from Barcelona, Rome (Civitavecchia), Genoa and Marseille. The Eastern Mediterranean is also well served, with sailings routing through Piraeus (Athens), Valletta, Marmaris and beyond.
The western circuit is the most heavily sailed route in the region. Itineraries typically combine ports in Spain, France and Italy, giving you a mix of city culture and coastal scenery across the week. Barcelona is the most popular embarkation port, with sailings also departing from Rome (Civitavecchia) and Genoa. If you are looking for Mediterranean cruises in 2027, the western route has some of the widest choice across lines and cabin grades.
Eastern itineraries tend to focus on Greece and the wider Aegean, with Piraeus (Athens) serving as the main gateway. Valletta, Malta appears regularly as a port of call or disembarkation point — a compact, walled city that rewards a few hours ashore. Naples, Palermo and Ravenna also feature across the mix of sailings.
MSC Cruises has the widest selection of 7-night Mediterranean departures, making it the most popular choice by volume. Costa Cruises follows closely, with a strong roster of sailings from Italian home ports. Explora Journeys brings a more premium, ocean-yacht style to the region. Royal Caribbean and Norwegian Cruise Line both offer lively, activity-focused ships, while Regent Seven Seas Cruises covers the luxury end with all-inclusive fares. Azamara, Oceania Cruises and The Ritz-Carlton Yacht Collection round out the choice for travellers who want something more intimate.
Costa Toscana is one of the standout ships in the Costa Cruises fleet for a Mediterranean week. Its restaurant Archipelago brings together 3 Michelin-starred chefs — Barbieri, Darroze and León — in a 12-course tasting experience that has no direct equivalent on any other Costa ship. The Ferrari Spazio Bollicine bar serves Ferrari wines and champagne in an exclusive setting you will not find elsewhere in the fleet. For spa lovers, the Solemio Spa covers 4,500 m² and includes a thalassotherapy pool, salt grotto and snow cave. View Costa Toscana cabin grades and deck plans:
Costa Fascinosa takes its design cue from Italian cinema, with interiors inspired by Fellini and Visconti — think gold leaf detailing and deep ruby tones throughout the ship. The Samsara Spa covers 6,000 m² across 2 decks and includes a thalassotherapy pool, with over 100 spa-access cabins available for guests who want that connection to the wellness areas built into their accommodation. Like Costa Toscana, Fascinosa carries the Archipelago restaurant with 3 Michelin-starred chefs on board. The three-deck theatre is one of the most dramatic at sea. See Costa Fascinosa cabins and deck plans:
Cunard’s Queen Elizabeth brings a distinctly British character to the Mediterranean. Art deco design runs throughout the ship — chandeliers, sweeping staircases and a grand lobby that reflect ocean travel from another era. The Royal Court Theatre stages West End-calibre productions, and Gala evenings in the Queens Room ballroom feature live orchestral dancing. Dining spans the Britannia restaurant through to Princess Grill and Queens Grill, with Cunard’s daily white-gloved afternoon tea service available throughout. Explore Queen Elizabeth cabin grades and deck plans:
Costa Pacifica is built around a music theme — from the Grand Bar Rhapsody at the heart of the ship, decorated with musical notes and chords, to an onboard recording studio where guests can lay down their own CD. That feature is unique across ocean cruising; no other ship at sea currently offers it. The Samsara Spa runs to 6,000 m² across 2 decks, with a glass-fronted gym giving panoramic sea views as you work out. View Costa Pacifica cabins and deck plans to compare grades and find the right fit for your sailing.
MSC Seaview is purpose-built for warm-weather sailing in the Mediterranean, with a promenade running along the lower deck that puts you close to the waterline. The ship carries a wide range of MSC sailings including itineraries well suited to families and couples alike. See MSC Seaview cabin grades and deck plans to explore your options.
Several cruise lines sailing the Mediterranean offer fare tiers that include drinks, dining and entertainment as standard. Costa Cruises offers fare types such as All Inclusive and Comfort Plus, which cover full board and unlimited drinks packages, as well as last-minute and flash-sale fares for more flexible travellers. Royal Caribbean offers fare types such as last-minute fares and early-booking options. Explora Journeys builds flights, private transfers and hotel stays into its Sky & Sea fare for a fully packaged experience. The right tier depends on how you like to travel — our team can walk you through what each one covers before you book.
Prices start from £332 pp* for a 7-night sailing, which puts a full week in the Mediterranean within reach of a wide range of budgets. Discounts are available on selected sailings — up to 49% off the price previously listed for that cabin grade on that sailing, though that maximum applies to a single departure; most reduced sailings are around 10% off. Choosing your cabin grade carefully and knowing which fare tier suits you makes a meaningful difference to what you get for your money. Our Mediterranean cruise deals page collects the strongest offers available.
All 7-night Mediterranean sailings depart from ports in Spain, Italy, France or Greece, so a flight from the UK is part of the journey. The good news is that Cruise1st can put that together for you. As part of a Cruise1st Package, we book your flights, any hotel you need the night before departure, transfers between the airport and the port, and your return leg — all on one booking. If your itinerary is one-way and ends in a different port from where it started, we handle the return flight from there too.
Some sailings ending in Rome, Piraeus (Athens), Valletta or Marseille make a natural extension possible — a night or two in the disembarkation city before flying home, which we can add to the same booking.
Cruise1st is one of the UK’s leading cruise specialists — we sell cruises and cruise-inclusive packages, not package holidays with a cruise added on. That means our team knows these ships and routes in detail, and can advise on cabin grades, fare inclusions and itinerary shape before you commit. We can build flights, hotels, tours, transfers and insurance around your cruise as a bundle or a fully custom holiday. Call us, and one of our cruise experts will take care of it.
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If 7 nights feels like the right shape but you want to explore other options, 14-day Mediterranean cruises from Southampton are a natural next step for those who want more time in the region. For a shorter taster, 3-day mini cruises from Southampton offer a long weekend at sea. All 7-night cruises — beyond the Mediterranean — are also worth exploring if you are open on destination. Norwegian Cruise Line fans may also want to look at all-inclusive Norwegian Fjords cruises in 2027 as an alternative for a different kind of 7-night sailing. For a broader view of the region, our Mediterranean cruises from the UK page covers every duration and departure port.
*Prices are per person based on 2 people sharing, and are subject to change. This price is not kept up to date and therefore does not reflect live pricing and availability. Prices and any discounts shown were checked on 14 October 2026.
Where a discount is shown, it is a reduction from the price previously listed for that cabin grade on that sailing, not a comparison between cabin grades or against a brochure rate.
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7 Day Mediterranean Cruises