2026/2027 SAILINGS OPEN!
The Western Mediterranean is one of the great cruise destinations — sun-soaked coastlines, historic cities and the kind of sailing that needs no airport at either end, because every departure here leaves from Southampton. Cruise1st is one of the UK’s leading cruise specialists, and our team can help you choose the right ship, the right cabin grade and the right fare for the way you like to travel. If you want flights, hotels, transfers or tours built around your cruise, we put everything on one booking through our Cruise1st Packages. Real expert advice, one call.

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84 cruises
Western Mediterranean from Southampton, England with the Regal Princess


Cruise Only
Save up to £600 per room!
From / To Southampton, England
Regal Princess
30 Apr 2027
15 nights
No Alternative Dates
Best Price Guarantee
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Western Mediterranean from Southampton, England with the Celebrity Apex


Cruise Only
Up to 75% off the 2nd guest plus up to $700 Onboard Spend!
From / To Southampton, England
Celebrity Apex
from £57 – £134 off when you book online
11 Sep 2027
14 nights
No Alternative Dates
Luxury No Fly Western Mediterranean


Cruise Only
Save up to £600 per room!
From / To Southampton, England
Sky Princess
7 Aug 2027
14 nights
Luxury No Fly Mediterranean Adventurer


Cruise Only
Save up to £600 per room!
From / To Southampton, England
Sky Princess
29 Mar 2027
14 nights
No Fly Western Mediterranean


Cruise Only
£500 off per Balcony cabin!
From / To Southampton, England
Britannia
5 May 2028
14 nights
Western Mediterranean from Southampton, England with the Arvia


Cruise Only
£500 off per Balcony cabin!
From / To Southampton, England
Arvia
4 Jul 2027
14 nights
Western Mediterranean from Southampton, England with the Arvia


Cruise Only
£500 off per Balcony cabin!
From / To Southampton, England
Arvia
9 May 2027
14 nights
Luxury No Fly Western Mediterranean


Cruise Only
Enjoy 10% off selected 2027 voyages
From / To Southampton, England
Queen Anne
Full board
7 Apr 2027
14 nights
No Alternative Dates
Western Mediterranean from Southampton, England with the Arcadia


Cruise Only
£500 off per Balcony cabin!
From / To Southampton, England
Arcadia
Adults Only
14 Aug 2028
14 nights
No Alternative Dates
Western Mediterranean from Southampton, England with the Ventura


Cruise Only
£500 off per Balcony cabin!
From / To Southampton, England
Ventura
30 Sep 2028
14 nights
No Alternative Dates
Drive or take the train to Southampton, walk on board, and wake up at sea the next morning — no check-in queues, no luggage allowances, no airport transfers. Every sailing departs from Southampton, which means the holiday starts the moment you step aboard. The Western Mediterranean is the most popular destination in this collection, followed by broader Mediterranean itineraries, so the choice of routes, ships and durations is wide. Sailings range from 5 nights to 82 nights, with a median of 16 nights — long enough to call at several ports without feeling rushed.
Around 66 of the sailings are round trips, returning to Southampton so there is nothing to arrange at the other end. The remaining 27 are one-way itineraries, ending at ports such as Barcelona, Rome (Civitavecchia) or Alicante — on those, you will need a flight home, and our team can book that alongside hotels and transfers so the whole journey is covered.
The destinations divide neatly into four groups, from the busy southern European routes that make up the bulk of the collection to the handful of longer sailings that reach well beyond the Mediterranean.
The Western Mediterranean is where most of these sailings are concentrated, covering the classic sweep of southern European coastline. Broader Mediterranean itineraries add further variety, and a small number of sailings reach the Canary Islands — a popular extension for those who want warm weather and volcanic scenery alongside the European ports. Ports of call in this group include Barcelona, Rome (Civitavecchia), Alicante, Marseille and Piraeus (Athens) — a broad mix of cultures and landscapes across a single voyage.
A small number of sailings cross into Transatlantic territory — longer voyages that suit those who want the experience of an ocean crossing rather than a port-hopping itinerary. Some of these end at Fort Lauderdale (Port Everglades) in Florida; it is worth noting that Fort Lauderdale and Miami are about half an hour apart, so a Florida trip can potentially continue from either port. A couple of sailings also dip into North Africa, adding a different dimension to a Mediterranean voyage.
A handful of sailings stay closer to home, exploring England and the British coastline — a good option for a shorter break or for those new to cruising who want to ease in gently before committing to a longer Mediterranean voyage.
P&O Cruises has the largest share of sailings in this collection, which makes sense — Southampton is effectively P&O’s home port, and the line has shaped its entire programme around no-fly departures from here. Cunard Line is the second most prominent, offering a more formal, classic style of ocean travel. MSC Cruises brings a European flavour, Fred Olsen Cruise Lines tends to suit those who prefer a smaller, more intimate ship, and Princess Cruises and Celebrity Cruises round out the choice for those who want a more resort-style experience. If you are weighing up which line suits you best, our cruise experts can talk you through the differences — call before you book and you will not be speaking to a general travel agent.
Several well-known ships sail this collection. Here is what stands out on the ones with the most departures.
Arcadia is a mid-sized P&O ship with a distinctly grown-up feel — it is an adults-only vessel, so the atmosphere on board is calm and relaxed. The Palladium is a striking 3-tier theatre, and Marco Pierre White’s Ocean Grill is one of the standout dining options at sea. The hydro-therapy pool is a genuine draw for those who want to unwind between ports. If you are choosing a cabin, the Arcadia cabins and deck plans are worth a look before you decide:
Queen Elizabeth is the ship for those who want the classic ocean liner experience. Art deco design runs throughout — glittering chandeliers, sweeping staircases and a grand lobby that evokes the golden age of travel. The Royal Court Theatre stages West End-calibre productions, and Gala evenings in the Queens Room ballroom feature live orchestral dancing. Cunard’s famous white-gloved afternoon tea service runs daily. The tiered dining across Britannia, Princess Grill and Queen’s Grill means the level of service you get scales with the cabin grade you choose. See the Queen Elizabeth cabins and deck plans for the full picture:
Queen Victoria shares Cunard’s hallmarks — the tiered dining, the Gala evenings, the white-gloved afternoon tea — but has a couple of features unique to this ship. Its Royal Court Theatre is the first at sea to feature private boxes, giving a genuinely theatrical experience. The ballroom is the largest at sea. And if you are the sort of person who dislikes feeling the ship move, the Deluxe Inside Deck 1 cabin positions are specifically noted for minimal movement. Check the Queen Victoria cabins and deck plans before you book:
Aurora is a mid-sized, classic ship with a distinctly British character — a good fit for those who want a relaxed, familiar atmosphere on a Western Mediterranean sailing. You can check the Aurora cabins and deck plans to compare grades before booking.
Britannia was named by Queen Elizabeth II in 2015 and sails year-round from Southampton. With 13 restaurants and cafés — including menus from Marco Pierre White, Atul Kochhar and James Martin — it is one of the most celebrated dining fleets afloat. The Headliners Theatre uses LED immersive technology, and the Limelight Club offers an intimate cabaret setting. The Britannia cabins and deck plans page covers every grade from inside to suite.
Arvia is P&O’s newest and largest ship, designed around sunny-weather cruising. If you are interested in how the cabins are laid out across the ship, the Arvia cabins and deck plans give a full breakdown.
MSC Meraviglia and MSC Virtuosa bring a large-ship, European resort feel to this collection. Both offer a wide range of dining, entertainment and cabin options across multiple decks. The MSC Meraviglia cabins and deck plans and MSC Virtuosa cabins and deck plans are useful if you are comparing grades across the MSC fleet.
Sky Princess brings Princess Cruises’ modern resort style to these routes. The Sky Princess cabins and deck plans cover grades from inside to suite — worth a look if you are planning around a specific cabin type or deck position.
Fare inclusions vary by cruise line, and knowing what is in the price before you book saves surprises on board.
Cunard offers several fare tiers on these sailings. The flexible Cunard Fare gives you the choice of stateroom number, priority for upgrades, a low 15% deposit with flexible balance payment, and the ability to amend your booking up to the balance due date — it also includes complimentary shuttle buses at ports. Fare types such as a car parking option, a coach travel option and on-board credit combinations are also available, so you can match the fare to how you are getting to Southampton. If you prefer the lowest possible price and are happy to pay in full at booking and accept a pre-allocated stateroom, the Saver fare is worth considering for last-minute sailings.
Princess offers a Standard base fare alongside the Princess Plus package, which bundles casual dining meals, beverages, MedallionNet Max Wi-Fi, crew appreciation, unlimited digital photographs and reserved theatre seating into one price. For those who want everything arranged in advance rather than paying for extras on board, Plus is the more straightforward option.
Celebrity’s fare structure runs from a base rate — covering the cruise itself with full access to dining and entertainment — through an All Inclusive tier that adds a classic drinks package and basic Wi-Fi, up to The Retreat, which covers premium drinks, premium Wi-Fi, suite accommodation, exclusive lounge and sundeck access, private dining and dedicated personal service.
Shorter sailings of around 7 nights are available in this collection, and they are popular with those who want a first Mediterranean cruise or a quick break without taking too much time off work. A 7-night Mediterranean cruise from Southampton typically calls at 3 or 4 ports, giving you a genuine taste of the region without the commitment of a longer voyage. If you want to go deeper — more ports, more time at sea — 14-day Mediterranean cruises from Southampton offer more variety within a still-manageable duration.
Some sailings in this collection carry a reduction from the price previously listed for that cabin grade — on the best example, that saving reaches up to 26%, though that applies to a single departure and most reduced sailings are closer to around 5% off. It is worth checking individual fares rather than assuming every sailing is discounted. Fare types such as Saver fares and last-minute offers can make a real difference to the overall cost, particularly if you are flexible on dates. Our team can tell you which sailings currently have the most movement on price when you call.
Cruise1st is one of the UK’s leading cruise specialists — not a general travel agent that happens to sell cruises. That matters when you are choosing between ships, cabin grades and fare tiers that look similar on paper but deliver quite different holidays in practice. Our cruise experts are on the phone before you book, and they know these ships and routes from the inside, not from a brochure.
Because all departures here leave from Southampton, most of Britain can reach the port by road or rail without needing a flight. That removes one of the biggest friction points in booking a cruise holiday. If you are making a longer trip of it — arriving the night before, adding a hotel in Southampton, or flying home from a one-way itinerary — our Cruise1st Packages bring flights, hotels, tours, transfers and insurance together on one booking, so there is nothing left to arrange separately. We are also ABTA and ATOL protected, and rated 4.5/5 on Trustpilot from over 7,000 reviews.
If you are looking at a broader range of cruises from Southampton — including other destinations and cruise lines — or want to see everything we offer across all cruises, both are a good place to explore. You can also browse 2027 cruises from Southampton if you are planning ahead, or consider a shorter break with a 3-day mini cruise from Southampton before committing to a longer voyage.
If you want to narrow the search — or open it up — there are several closely related options worth considering. Mediterranean cruises in 2027 covers the full Mediterranean programme across all departure ports. Norway cruises from the UK are a natural alternative for those drawn to cooler, dramatic scenery rather than the southern European sun. P&O Canary Islands cruises suit those who want guaranteed warmth with a straightforward sailing from Southampton. Princess Cruises 2027 sailings from Southampton are worth browsing if you have already decided on the line. And if you are open to the Mediterranean from a UK port but not fixed on Southampton, Mediterranean cruises from Southampton covers the broader picture, while cruises from the UK opens the full range of departure ports.
Istanbul is occasionally included on extended Mediterranean itineraries — if that port is on your wish list, the Istanbul cruise port guide has everything you need to plan time ashore.
Do I need to fly to join a Western Mediterranean cruise from Southampton?
How long are Western Mediterranean cruises from Southampton?
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Which cruise lines sail the Western Mediterranean from Southampton?
Western Mediterranean Cruises from Southampton