Panama Canal Cruises - Top Picks
This week, Cruise1st’s Top Picks spotlight the enchanting Panama Canal cruises, where you can delve into stunning landscapes and vibrant cultures. Experience the bustling charm of Colon, where the iconic Miraflores Locks reveal the engineering marvel of the Canal. Don’t miss a visit to the lush wonders of Gatun Lake, teeming with wildlife. Explore the historical allure of Panama City with its picturesque Casco Viejo district, filled with colourful colonial architecture. These trending adventures promise unforgettable memories among breathtaking vistas!
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44 cruises
Central America from Miami, Florida with the Brilliant Lady
Cruise Only
Up to $1000 savings + 70% OFF second sailor!
From Miami To Los Angeles
Brilliant Lady
Adults Only
Full board
26 Mar 2027
16 nights
Best Price Guarantee
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Luxury Panama Canal Ocean to Ocean Adventure
Cruise with Flight, Hotel
From Fort Lauderdale To Los Angeles
Star Princess
1 Apr 2027
21 nights
No Alternative Dates
Picturesque Panama Canal and Latin American Charms
Cruise with Flight, Hotel
Special Offer Available
From Los Angeles To Miami
Brilliant Lady
Adults Only
Full board
25 Nov 2027
20 nights
Central America from Los Angeles, California with the Celebrity Summit
Cruise Only
From Los Angeles To Boston
Celebrity Summit
from £33 – £53 off when you book online
18 Sep 2027
18 nights
No Alternative Dates
Central America from Tampa, Florida with the Celebrity Summit
Cruise Only
From Tampa To Los Angeles
Celebrity Summit
from £45 – £121 off when you book online
18 Apr 2027
15 nights
No Alternative Dates
Central America from Los Angeles, California with the Brilliant Lady
Cruise Only
Up to $1000 savings + 70% OFF second sailor!
From Los Angeles To Miami
Brilliant Lady
Adults Only
Full board
27 Nov 2027
17 nights
Central America from San Diego, California with the Serenade of the Seas
Cruise Only
From San Diego To Tampa
Serenade of the Seas
£32 off when you book online
7 Oct 2027
15 nights
No Alternative Dates
Luxury Panama Canal and Southern Caribbean
Cruise with Flight, Hotel
From / To Fort Lauderdale
Celebrity Ascent
All Inclusive
20 Nov 2026
15 nights
Caribbean Charms & Panama Passage with Miami Stay
Cruise with Flight, Hotel
From / To Fort Lauderdale
Celebrity Ascent
19 Nov 2027
15 nights
No Alternative Dates
Southern Caribbean from Fort Lauderdale (Port Everglades), Florida with the Celebrity Ascent
Cruise Only
From / To Fort Lauderdale
Celebrity Ascent
from £23 – £168 off when you book online
23 Nov 2026
11 nights