Panama Canal Cruises - Top Picks
This week, Cruise1st’s Top Picks spotlight the enchanting Panama Canal cruises, where you can delve into stunning landscapes and vibrant cultures. Experience the bustling charm of Colon, where the iconic Miraflores Locks reveal the engineering marvel of the Canal. Don’t miss a visit to the lush wonders of Gatun Lake, teeming with wildlife. Explore the historical allure of Panama City with its picturesque Casco Viejo district, filled with colourful colonial architecture. These trending adventures promise unforgettable memories among breathtaking vistas!
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52 cruises
Luxury Panama Canal Ocean to Ocean Adventure
Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From Fort Lauderdale To Los Angeles
Star Princess
1 Apr 2027
21 nights
No Alternative Dates
Best Price Guarantee
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Central America from Miami, Florida with the Brilliant Lady
Cruise Only
From Miami To Los Angeles
Brilliant Lady
Adults Only
26 Mar 2027
16 nights
Panama Canal Transit: Miami to Los Angeles
Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From Miami To Los Angeles
Brilliant Lady
Adults Only
19 Feb 2028
19 nights
No Alternative Dates
Central America from Los Angeles, California with the Celebrity Summit
Cruise Only
Up to 75% off the 2nd guest plus up to $700 Onboard Spend!
From Los Angeles To Boston
Celebrity Summit
from £32 – £269 off when you book online
18 Sep 2027
18 nights
No Alternative Dates
Picturesque Panama Canal and Latin American Charms
Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From Los Angeles To Miami
Brilliant Lady
Adults Only
25 Nov 2027
20 nights
No Alternative Dates
Central America from Tampa, Florida with the Celebrity Summit
Cruise Only
Up to 75% off the 2nd guest plus up to $700 Onboard Spend!
From Tampa To Los Angeles
Celebrity Summit
from £23 – £133 off when you book online
18 Apr 2027
15 nights
No Alternative Dates
Central America from Los Angeles, California with the Brilliant Lady
Cruise Only
From Los Angeles To Miami
Brilliant Lady
Adults Only
27 Nov 2027
17 nights
No Alternative Dates
Central America from San Diego, California with the Serenade of the Seas
Cruise Only
Up to £675 off your room and a Cyber Bonus of up to $100 Onboard Spending Money
From San Diego To Tampa
Serenade of the Seas
£41 off when you book online
7 Oct 2027
15 nights
No Alternative Dates
Central America from Tampa, Florida with the Serenade of the Seas
Cruise Only
Up to £675 off your room and a Cyber Bonus of up to $100 Onboard Spending Money
From Tampa To Los Angeles
Serenade of the Seas
from £25 – £46 off when you book online
22 Apr 2028
15 nights
No Alternative Dates
Luxury Panama Canal and Southern Caribbean
Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Fort Lauderdale
Celebrity Ascent
All Inclusive
20 Nov 2026
15 nights