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South America Cruises - Top Picks

Dive into the vibrant allure of South America with Cruise1st’s Top Picks for the week! Experience the rhythm of Rio de Janeiro, where the stunning beaches of Copacabana meet the iconic Sugarloaf Mountain. Explore the lush Amazon rainforest, teeming with exotic wildlife, or marvel at the breathtaking landscapes of Patagonia, from the jagged peaks of Los Glaciares National Park to the stunning vistas of Torres del Paine. Discover the gastronomic delights of Buenos Aires, making your cruise an unforgettable adventure!

View All South America Cruises
South America Cruises - Top Picks

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Departure Dates

Trip Duration

Cabin Category

Price

£

£

Trip price per person based on 2 persons trip

Destination

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777

393

41

765

985

3397

800

1771

774

3443

Cruise lines

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77

43

28

37

254

33

3

57

24

4

Ships

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24

29

29

34

Starting Port

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20

3

123

2

35

2

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​

19

98

3

27

11

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8

31

15

53

35

777 cruises

Brazil from Rio de Janeiro, Brazil with the MSC Musica

MSC Cruises

Cruise Only

Save up to 30% OFF!

From / To Rio de Janeiro

MSC Musica

Full board

Tips

5 Jan 2027

7 nights

Inside from

£620

pp

Was £689

Outside from

£683

pp

Was £759

Balcony from

£737

pp

Was £819

MSC Yacht Club from

£935

pp

Was £1,039

Best Price Guarantee

Learn more

South America from Santos, Brazil with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Santos (São Paulo)

MSC Meraviglia

Full board

Tips

up to £32 off when you book online

28 Nov 2027

7 nights

Inside from

£651

pp

Was £723

Outside from

£741

pp

Was £823

Balcony from

£966

pp

Was £1,073

MSC Yacht Club from

£1,587

pp

Was £1,763

South America from Santos, Brazil with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Santos (São Paulo)

MSC Meraviglia

Full board

Tips

up to £33 off when you book online

30 Jan 2028

7 nights

Inside from

£651

pp

Was £723

Outside from

£777

pp

Was £863

Balcony from

£984

pp

Was £1,093

MSC Yacht Club from

£1,632

pp

Was £1,813

South America from Camboriu, Brazil with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Camboriú

MSC Meraviglia

Full board

Tips

up to £32 off when you book online

29 Nov 2027

7 nights

Inside from

£651

pp

Was £723

Outside from

£741

pp

Was £823

Balcony from

£966

pp

Was £1,073

MSC Yacht Club from

£1,587

pp

Was £1,763

South America from Buenos Aires, Argentina with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Buenos Aires

MSC Meraviglia

Full board

Tips

up to £32 off when you book online

2 Dec 2027

7 nights

Inside from

£651

pp

Was £723

Outside from

£741

pp

Was £823

Balcony from

£966

pp

Was £1,073

MSC Yacht Club from

£1,587

pp

Was £1,763

South America from Camboriu, Brazil with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Camboriú

MSC Meraviglia

Full board

Tips

up to £33 off when you book online

31 Jan 2028

7 nights

Inside from

£687

pp

Was £763

Outside from

£777

pp

Was £863

Balcony from

£1,002

pp

Was £1,113

MSC Yacht Club from

£1,632

pp

Was £1,813

South America from Santiago de Chile, Chile with the Majestic Princess

Princess Cruises

Cruise Only

Save up to £600 per room!

From Santiago de Chile To Buenos Aires

Majestic Princess

6 Dec 2027

15 nights

No Alternative Dates

Inside from

£1,710

pp

Was £2,165

Balcony from

£1,930

pp

Was £2,573

Suite from

£2,320

pp

Was £4,070

South America from Buenos Aires, Argentina with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Buenos Aires

MSC Meraviglia

Full board

Tips

up to £33 off when you book online

27 Jan 2028

7 nights

Inside from

£687

pp

Was £763

Outside from

£777

pp

Was £863

Balcony from

£1,002

pp

Was £1,113

MSC Yacht Club from

£1,632

pp

Was £1,813

South America from Buenos Aires, Argentina with the Majestic Princess

Princess Cruises

Cruise Only

New Caribbean 2028 Collection

From Buenos Aires To Valparaíso (Santiago)

Majestic Princess

7 Dec 2026

15 nights

No Alternative Dates

Inside from

£1,901

pp

Balcony from

£1,963

pp

Suite from

£2,604

pp

South America from Buenos Aires, Argentina with the MSC Meraviglia

MSC Cruises

Cruise Only

From / To Buenos Aires

MSC Meraviglia

Full board

Tips

up to £39 off when you book online

23 Dec 2027

7 nights

No Alternative Dates

Inside from

£815

pp

Was £906

Outside from

£941

pp

Was £1,046

Balcony from

£1,155

pp

Was £1,283

MSC Yacht Club from

£1,939

pp

Was £2,154

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