South America Cruises - Top Picks
Dive into the vibrant allure of South America with Cruise1st’s Top Picks for the week! Experience the rhythm of Rio de Janeiro, where the stunning beaches of Copacabana meet the iconic Sugarloaf Mountain. Explore the lush Amazon rainforest, teeming with exotic wildlife, or marvel at the breathtaking landscapes of Patagonia, from the jagged peaks of Los Glaciares National Park to the stunning vistas of Torres del Paine. Discover the gastronomic delights of Buenos Aires, making your cruise an unforgettable adventure!
Stopover
Arrival port
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794 cruises
Brazil from Rio de Janeiro, Brazil with the MSC Musica
Cruise Only
Extra 2% Discount!
From / To Rio de Janeiro
MSC Musica
Full board
Tips
up to £60 off when you book online
2 Mar 2027
7 nights
Best Price Guarantee
Learn more
South America from Santos, Brazil with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Santos (São Paulo)
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
12 Dec 2027
7 nights
South America from Santos, Brazil with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Santos (São Paulo)
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
12 Mar 2028
7 nights
South America from Camboriu, Brazil with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Camboriú
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
13 Dec 2027
7 nights
South America from Buenos Aires, Argentina with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Buenos Aires
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
9 Dec 2027
7 nights
South America from Camboriu, Brazil with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Camboriú
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
13 Mar 2028
7 nights
South America from Buenos Aires, Argentina with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Buenos Aires
MSC Meraviglia
Full board
Tips
up to £32 off when you book online
9 Mar 2028
7 nights
Luxury Patagonia & Cape Horn Discovery Cruise
Cruise with Flight, Hotel
From Santiago de Chile To Buenos Aires
Majestic Princess
4 Dec 2027
18 nights
No Alternative Dates
South America from Santos, Brazil with the MSC Meraviglia
Cruise Only
Extra 2% Discount!
From / To Santos (São Paulo)
MSC Meraviglia
Full board
Tips
up to £44 off when you book online
19 Dec 2027
8 nights
No Alternative Dates
South America from Santiago de Chile, Chile with the Majestic Princess
Cruise Only
Up to $500 Onboard Spend!
From Santiago de Chile To Buenos Aires
Majestic Princess
6 Dec 2027
15 nights