The Mediterranean is one of the world's most sailed regions, and in 2027 you can fly out, board in Spain, Italy or Greece, and let Cruise1st handle everything around it. As one of the UK's leading cruise specialists, we put the flights, hotels, transfers and cruise on a single booking — so the holiday fits together before you leave home. Our expert team can help you pick the right cabin grade and fare type for your budget, whether you want a short 6-night break or a longer voyage of up to 23 nights.
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Greek Island Glow with Cruise1st TV's Derek Marks


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Piraeus (Athens), Greece
Scarlet Lady
Adults Only
7 Aug 2027
8 nights
No Alternative Dates
Best Price Guarantee
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Odyssey of Greece & Turkey


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Rome
Odyssey of the Seas
30 Jul 2027
9 nights
No Alternative Dates
Western Mediterranean from Barcelona with the MSC World Europa


Cruise with Flight
Save up to 30% OFF!
From / To Barcelona
MSC World Europa
Full board
Tips
up to £55 off when you book online
15 May 2027
7 nights
The Italian Riviera, Sicily & Malta With Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
MSC World Asia
Tips
10 Mar 2027
9 nights
No Alternative Dates
Legends of the Western Med Cruise


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
Legend of the Seas
23 Oct 2027
8 nights
No Alternative Dates
Western Mediterranean from Barcelona with the MSC Seaview


Cruise with Flight
Save up to 30% OFF!
From / To Barcelona
MSC Seaview
Full board
Tips
from £20 – £36 off when you book online
31 Oct 2027
7 nights
Luxury Aegean Dreams & Italian Delights


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From Rome To Piraeus (Athens), Greece
Sun Princess
16 Apr 2027
9 nights
No Alternative Dates
Western Mediterranean from Barcelona with the MSC World Asia


Cruise with Flight
Save up to 30% OFF!
From / To Barcelona
MSC World Asia
Full board
Tips
from £21 – £56 off when you book online
29 Oct 2027
7 nights
Santorini, Mykonos & Rome With Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Rome
MSC Divina
Full board
Tips
5 May 2027
9 nights
Legends of the Western Mediterranean With Barcelona Stay


Cruise with Flight, Hotel
Black Friday Sale: Savings of up to £1,000 per couple!
From / To Barcelona
Legend of the Seas
17 Sep 2027
9 nights
No Alternative Dates
The appeal is straightforward: you fly out, board in the heart of the Mediterranean, and spend every day somewhere new without repeating a port. For most British travellers these sailings start in the Mediterranean itself — in Spain, Italy or Greece — which means the ship is already surrounded by the scenery you came for from the very first morning. Cruise1st brings the flights, transfers and any hotels either side together as a Cruise1st Package, so you are not left to piece it together yourself.
A Mediterranean fly cruise is a cruise holiday where your flight is included as part of the booking — you fly to your embarkation port, join the ship, and sail from there. On these sailings the ship departs from a port in the Mediterranean rather than from the UK, which means the itinerary begins immediately in the region you are visiting. Cruise1st can also arrange hotels the night before departure, transfers between the airport and the port, and travel insurance, so the whole trip sits on one booking.
Sailings in 2027 range from 6 to 23 nights, with a median of 9 nights — long enough to take in several destinations, short enough to fit into a standard annual leave allowance. A good proportion of the itineraries are one-way, meaning the ship ends its voyage at a different port from the one it started at. On those sailings a return flight home is part of the arrangement, and our team will make sure it is covered.
The Western Mediterranean is where most of the 2027 fly-cruise programme is concentrated. Itineraries in this area take in the coasts of Spain, France and Italy, with embarkation ports including Barcelona, Rome (Civitavecchia), Marseille and Genoa. These routes are the most popular with British fly-cruise travellers and the widest range of cruise lines and ships operate them.
The broader Mediterranean category covers itineraries that move across both east and west, often combining ports in Italy with those in Croatia, Montenegro or the Adriatic coast — a good choice if you want variety across a single voyage.
The Eastern Mediterranean is well represented too, with sailings departing from Piraeus (Athens) and calling at ports in Greece and Turkey. Istanbul appears as a disembarkation port on some itineraries, making it possible to end your cruise with a city stay before flying home — and Cruise1st can arrange that hotel too. Valletta in Malta features on some of these routes as well; you can explore Valletta further on our dedicated port page. A small number of sailings extend beyond the Mediterranean into Transatlantic waters — worth considering if you are after something more ambitious.
The main embarkation ports for Mediterranean fly cruises in 2027 are Barcelona in Spain, Piraeus (the port for Athens) in Greece, and Rome (Civitavecchia) in Italy. Marseille in France and the Italian ports of Venice and Savona also feature. Because the flight is included, Cruise1st can match you to the departure airport closest to you — our team will sort the connection from your home city to whichever Mediterranean port your chosen sailing uses.
Disembarkation ports follow a similar pattern: Rome, Piraeus (Athens), Naples and Palma de Mallorca are among the common end points, alongside Istanbul and Genoa. On one-way itineraries your return flight departs from the disembarkation port — we will book that as part of the same package.
MSC Cruises has the largest presence in the 2027 Mediterranean fly-cruise programme, making it the most popular line for this destination and year. Costa Cruises is close behind, with a strong Italian flavour to its fleet and itineraries. Royal Caribbean, Celebrity Cruises and Princess Cruises each bring their own style to the region, from family-focused mega-ships to premium and contemporary options. Azamara, Explora Journeys, Oceania Cruises and Regent Seven Seas Cruises round out the luxury and boutique end of the market. Fare types vary by line and include options such as early-booking bonuses, last-minute fares and bundled all-inclusive tiers — our team will explain what each one covers before you commit.
Sun Princess is the standout new arrival. The ship’s centrepiece is The Dome, a multi-level glass-enclosed deck inspired by Santorini terraces, with an indoor/outdoor pool that converts into an evening entertainment venue after dark. With 29 dining and bar options — more than any other Princess ship — including the three-storey Horizons Dining Room, Sun Princess is built for guests who take food seriously.
Azamara Onward takes a very different approach. At around 692 guests she is small enough to dock at 167 ports that larger ships cannot reach, and Azamara’s signature overnight and late-night port stays mean you genuinely get to explore each destination rather than simply photograph it. Dining runs to Prime C Steakhouse, Aqualina Italian restaurant and a Caviar & Champagne Bar. Cabin choices on Azamara Onward range from a 14.7 m² inside cabin to the 52 m² Club World Owner’s Suite — see the Azamara Onward cabins and deck plans for the full breakdown.
Mariner of the Seas went through Royal Caribbean’s Royal Amplified refit in 2023, adding a FlowRider surf simulator, The Perfect Storm waterslides and a laser tag arena. The Royal Promenade — an indoor boulevard of bars, restaurants and live entertainment running the length of the ship — is what this Voyager-class vessel is known for. Dining options include Jamie’s Italian, Chops Grille steakhouse and Izumi sushi, across 11 venues in total. Check the Mariner of the Seas cabins and deck plans when you are ready to choose your stateroom.
Costa Deliziosa is the only Costa ship with dedicated golf facilities — a simulator and an outdoor putting green on deck. The Samsara Spa covers 3,500 m² across two decks, with a thalassotherapy pool and thermal suite. A retractable glass roof over the main pool deck means open-air evenings whatever the weather, with a giant cinema screen for film nights. See the Costa Deliziosa cabins and deck plans for more detail. Also sailing with Costa in 2027 are Costa Toscana — with deck plans — and Costa Favolosa, whose cabins and deck plans are also on the site.
MSC Sinfonia is a Lirica-class ship at 65,542 GT — compact enough to access smaller harbours that the mega-ships cannot. She carries 94 balcony cabins, a top-deck water park with slides, and an Aurea Spa with thermal suite. The Teatro San Carlo hosts Broadway-style shows, and dedicated LEGO and Chicco children’s zones make her a strong choice for families. See the MSC Sinfonia cabins and deck plans for the full cabin listing.
Other ships sailing Mediterranean fly-cruise itineraries in 2027 include Celebrity Infinity (with cabin and deck plan details here), Costa Fascinosa (see the Costa Fascinosa cabins and deck plans), and EXPLORA II by Explora Journeys (with cabin grades including the 183 m² Owner’s Residence detailed here).
What your cruise fare covers depends on the line. With Costa Cruises, options run from a pared-back Flash fare — which includes full board at a keen price and lets you add a drinks package later — up to the Comfort Plus tier, which bundles full board, unlimited drinks and 24-hour room service into one price. The All Inclusive tier adds an Italian drinks and indulgence package on top of everything else.
With Royal Caribbean, fare types include a standard Cruise Fare, a Solo/Single Fare for guests travelling alone, and last-minute offers on selected sailings. The line also runs promotional fare types — such as reduced fares for third and fourth guests — though these are subject to availability and booking windows; our team will tell you what is currently on offer.
Celebrity Cruises structures its fares in three tiers. The best-rate fare covers dining, entertainment and onboard activities, leaving drinks and Wi-Fi as extras you choose yourself. The best-value fare bundles a classic drinks package and basic Wi-Fi into the base price. The Retreat tier — for suite guests — adds premium drinks, premium Wi-Fi, exclusive lounge access and private dining.
Cruise1st is one of the UK’s leading cruise specialists, which means the team booking your holiday knows these ships and itineraries in real depth — not a general travel agent picking from a brochure. We can put together a Cruise1st Package that combines your cruise with flights, hotels, transfers, tours and insurance, all on one booking reference. That matters when the cruise ends in a different city from the one it started in: your hotel for the night, your transfer to the airport and your flight home are all sorted before you leave the UK.
Our expert advisers are available by phone before you book, to help you weigh up cabin grades, compare fare inclusions and work out which itinerary actually suits your travel dates. Cruise1st is ABTA and ATOL protected, and holds a Trustpilot rating of 4.5/5 from over 7,000 reviews. Browse the full range of cruises on our site, or explore our dedicated Mediterranean fly cruises hub for the wider programme.
If you prefer to sail without flying, it is worth knowing that a small number of Mediterranean-adjacent sailings do depart from UK ports — most of Britain can reach Southampton, Liverpool or Dover by road or rail. However, for the 2027 Mediterranean programme the great majority of itineraries are fly-cruise, departing from ports in Spain, Italy and Greece. See Mediterranean cruises from Southampton in 2027 for the no-fly options.
If you want to compare before you decide, the full 2027 Mediterranean cruises listing covers all routes including those without a flight. For something with more inclusions, Mediterranean all-inclusive cruises in 2027 narrows the search to bundled fares. Individual lines have their own 2027 pages: MSC Cruises in 2027, MSC fly cruises in 2027, Celebrity Cruises in 2027, and Celebrity 2027 cruises from Southampton are all worth a look. For Princess, see Princess Cruises 2027 from Southampton. The broader 2027 cruises listing covers every region and every line if you are still weighing up the alternatives.
Prefer a different destination altogether? Caribbean fly cruises and all-inclusive fly Caribbean cruises in 2027 are popular alternatives for travellers who want guaranteed warmth. All fly cruises in 2027 gives you the widest possible view of the programme.
Can I Travel Solo on a Mediterranean Fly Cruise in 2027?
Do I Need a Visa to Cruise the Mediterranean in 2027?
How Long Are Mediterranean Fly Cruises in 2027?
What Happens If My Fly Cruise Is One-Way?
What Is Included in a Mediterranean Fly Cruise Package?
Mediterranean Fly Cruises in 2027