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Panama City Cruises up to -33%

Cruise to Panama City with Cruise1st and enjoy unparalleled luxury, top-notch amenities, and exclusive deals. Book your dream cruise today!

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65 cruises

Picturesque Panama Canal and Latin American Charms

Cruise1st Package

Cruise with Flight, Hotel

From Los Angeles To Miami

Brilliant Lady

Adults Only

Full board

Entertainment included

Starlink Internet

25 Nov 2027

20 nights

Inside

from

£2,499

pp

Outside

from

£2,599

pp

Balcony

from

£2,899

pp

Suite

from

£7,599

pp

£7,834

Best Price Guarantee

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Central America from Los Angeles, California with the Brilliant Lady

Virgin Voyages

Cruise Only

From Los Angeles To Miami

Brilliant Lady

Adults Only

Full board

All-Inclusive Ship

Dine Like a Rock Star

Entertainment included

Starlink Internet

Status Match Programme

29 Oct 2026

17 nights

Inside

from

£1,259

pp

£1,415

Outside

from

£1,387

pp

£1,801

Balcony

from

£1,838

pp

£2,703

Suite

from

£7,116

pp

£7,735

World Cruise from Miami, Florida with the Azamara Onward

Azamara

Cruise Only

From Miami To Auckland

Azamara Onward

All Inclusive

Drinks

Tips

All-Inclusive Ship

Entertainment included

Premium Cruise Line

Starlink Internet

5 Jan 2028

41 nights

No Alternative Dates

Inside

from

£9,253

pp

£13,810

Outside

from

£9,992

pp

£14,913

Balcony

from

£11,499

pp

£17,423

Suite

from

£17,615

pp

£27,523

World Cruise from Miami, Florida with the Azamara Onward

Azamara

Cruise Only

From Miami To Sydney, Australia

Azamara Onward

All Inclusive

Drinks

Tips

All-Inclusive Ship

Entertainment included

Premium Cruise Line

Starlink Internet

5 Jan 2028

56 nights

No Alternative Dates

Inside

from

£13,554

pp

£20,230

Outside

from

£14,927

pp

£22,279

Balcony

from

£17,029

pp

£25,802

Suite

from

£25,429

pp

£39,733

World Cruise from Miami, Florida with the Azamara Onward

Azamara

Cruise Only

From Miami To Hong Kong

Azamara Onward

All Inclusive

Drinks

Tips

All-Inclusive Ship

Entertainment included

Premium Cruise Line

Starlink Internet

5 Jan 2028

83 nights

No Alternative Dates

Inside

from

£20,907

pp

£31,204

Outside

from

£22,971

pp

£34,805

Balcony

from

£26,091

pp

£40,140

Suite

from

£38,600

pp

£60,313

World Cruise from Miami, Florida with the Azamara Onward

Azamara

Cruise Only

From Miami To Pireus (Athens), Greece

Azamara Onward

All Inclusive

Drinks

Tips

All-Inclusive Ship

Entertainment included

Premium Cruise Line

Starlink Internet

5 Jan 2028

176 nights

No Alternative Dates

Inside

from

£41,048

pp

£43,668

Outside

from

£42,479

pp

£45,190

Balcony

from

£49,631

pp

£52,799

Suite

from

£76,827

pp

£81,731

Transatlantic from Miami, Florida with the Azamara Onward

Azamara

Cruise Only

From Miami To Callao (Lima)

Azamara Onward

All Inclusive

Drinks

Tips

All-Inclusive Ship

Entertainment included

Premium Cruise Line

Starlink Internet

5 Jan 2028

14 nights

No Alternative Dates

Inside

from

£3,138

pp

£3,338

Outside

from

£3,503

pp

£3,727

Balcony

from

£4,050

pp

£4,309

Suite

from

£6,248

pp

£6,647

Central America from San Diego, California with the Norwegian Star

Norwegian Cruise Line

Cruise Only

From San Diego To Miami

Norwegian Star

Entertainment included

Family Friendly

Fun Cruise Line

Starlink Internet

Status Match Programme

13 Feb 2027

16 nights

No Alternative Dates

Inside

from

£1,514

pp

£1,594

Outside

from

£1,832

pp

£1,928

Balcony

from

£2,996

pp

£3,154

Suite

from

£4,411

pp

£4,693

Central America from Los Angeles, California with the Norwegian Joy

Norwegian Cruise Line

Cruise Only

From Los Angeles To Miami

Norwegian Joy

Entertainment included

Family Friendly

Fun Cruise Line

Starlink Internet

Status Match Programme

7 Oct 2026

16 nights

No Alternative Dates

Inside

from

£1,509

pp

£1,677

Outside

from

£1,742

pp

£1,980

Balcony

from

£2,336

pp

£2,625

Suite

from

£3,827

pp

£4,160

The Haven

from

£6,995

pp

£7,363

Central America from Los Angeles, California with the Norwegian Encore

Norwegian Cruise Line

Cruise Only

From Los Angeles To Miami

Norwegian Encore

Cabins Sleeping up to 5!

Entertainment included

Family Friendly

Fun Cruise Line

Starlink Internet

Status Match Programme

9 Jan 2028

15 nights

No Alternative Dates

Inside

from

£1,585

pp

£1,910

Outside

from

£2,146

pp

£2,495

Balcony

from

£2,777

pp

£3,156

The Haven

from

£8,511

pp

£9,152

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Explore the Vibrant City of Panama City, Panama

Panama City is a dynamic metropolis that beautifully blends modernity and historical charm, serving as the gateway to the incredible Panama Canal. This bustling capital is known for its stunning skyline, rich cultural heritage, and vibrant nightlife. Fun fact: Panama City is the only capital city in the world that boasts a national park—Metropolitan Natural Park—right within its borders! Visiting Panama City on a cruise allows you to experience its unique attractions while soaking in the stunning views of the canal and its surrounding landscapes.

Your Guide to Panama City, Panama

When cruising into Panama City, you’ll find a wealth of activities to enhance your visit. Here’s how to make the most of your time in this colourful destination:

  • Panama Canal Tour: One of the greatest highlights of visiting Panama City is the chance to take a guided tour of the Panama Canal. Witness the engineering marvel up close as you learn about its history and operations. Many cruises offer excursions that allow you to experience the locks in action.
  • Old Town (Casco Viejo): Visit Casco Viejo, the city’s UNESCO World Heritage site, boasting cobblestone streets, colonial architecture, and charming plazas. Explore its boutique shops, historical landmarks like the French Embassy, and sample local dishes at vibrant restaurants.
  • Metropolitan Natural Park: If you seek a nature fix, head to Metropolitan Natural Park, where you can hike through lush tropical forests and enjoy stunning views of the city skyline. Look out for fascinating wildlife, including monkeys and various bird species. Don’t forget to bring your camera!
  • Amador Causeway: Stroll along the Amador Causeway, a scenic promenade that offers gorgeous views of the Panama City skyline and the Pacific entrance of the canal. This area is perfect for walking or cycling, and you’ll find several restaurants and shops to explore.
  • Panama Canal Museum: Take time to visit the Panama Canal Museum, which showcases the canal’s history and significance. Exhibits include photographs, documents, and models that illustrate the canal’s construction and impact on global trade.

Nearby Harbours to Explore During Your Cruise

As you cruise to Panama City, you might also have the opportunity to visit several captivating ports. Here’s what to look forward to:

  • Cartagena, Colombia: Known for its colonial architecture and vibrant history, Cartagena is a UNESCO World Heritage site. Explore the old town, visit the Castillo San Felipe de Barajas, and indulge in fresh seafood at seaside restaurants.
  • Panama Canal, Panama: Experience the breathtaking transit of the Panama Canal. The canal connects the Atlantic and Pacific Oceans, and offers excursions that let you witness the stunning engineering of its locks.
  • Puerto Limon, Costa Rica: Puerto Limon serves as the gateway to Costa Rica’s lush rainforests and diverse wildlife. Take a tour to explore nearby wildlife reserves, experience the local culture, and discover beautiful beaches in the region.
  • Cabo San Lucas, Mexico: Renowned for its stunning beaches and nightlife, Cabo San Lucas is the perfect spot for relaxation and adventure. Enjoy water sports like snorkeling or diving, or take a boat tour to see the iconic El Arco rock formation.
  • Puerto Quetzal, Guatemala: This port serves as the connection to Antigua, a charming colonial town filled with cobblestone streets and vibrant markets. Explore the town’s historical sites or join a coffee plantation tour to learn about Guatemala’s famed coffee.

Regions Accessible When Visiting Panama City, Panama

A cruise to Panama City allows you to discover numerous exciting destinations throughout various regions. Here’s what awaits you:

  • Central America: Central America is a treasure trove of diverse cultures, stunning natural beauty, and vibrant wildlife. Explore countries like Costa Rica, Nicaragua, and Honduras, where lush rainforests and breathtaking landscapes await you.
  • South America: South America boasts incredible diversity in landscapes and cultures. Countries like Colombia, Peru, and Brazil offer vibrant cities, rich history, and iconic natural wonders, such as the Amazon rainforest and Machu Picchu.
  • Western Caribbean: The Western Caribbean is famous for its pristine beaches and turquoise waters. Explore the beautiful islands of Jamaica, Cozumel, and Grand Cayman, where you’ll find a mix of relaxation and adventure with plenty of activities to choose from.
  • Caribbean: The Caribbean is renowned for its idyllic islands and luxurious resorts. Discover the vibrant cultures of places like Barbados, St. Lucia, and the Bahamas, each offering unique experiences and breathtaking scenery.
  • Mexican Riviera: The Mexican Riviera stretches along the Pacific coast and includes stunning cities such as Acapulco and Puerto Vallarta. Experience beautiful beaches, delicious cuisine, and thrilling nightlife in this popular region.

Major Cruise Lines Visiting Panama City, Panama

  • Norwegian Cruise Line: Featuring Norwegian Jade and Norwegian Encore, Norwegian Cruise Line offers a dynamic onboard experience complemented by exciting itineraries. With a fleet of 21 ships, they typically depart from Miami or Los Angeles, ensuring fantastic visits to Panama City.
  • Oceania Cruises: Showcasing Insignia and Sirena, Oceania Cruises is known for its luxurious experiences and exceptional dining options. Their fleet of 8 ships usually departs from Miami or Panama City, providing wonderful journeys through the region.
  • Azamara: Highlighting Azamara Quest and Azamara Onward, Azamara offers immersive experiences with a focus on local culture and community engagement. Their fleet of 4 ships departs most often from Miami or Panama City for enriching voyages.
  • Regent Seven Seas Cruises: Featuring Seven Seas Grandeur and Seven Seas Splendor, Regent Seven Seas Cruises offers an ultra-luxury experience with all-inclusive amenities. Their fleet of 6 ships typically departs from Miami or Panama City, ensuring extraordinary journeys.

Visiting Panama City Throughout the Year

Every season in Panama City offers unique experiences for exploration and enjoyment. Here’s what to expect during your visit:

  • Winter (December, January, February): Winter temperatures in Panama City generally range from 21°C to 30°C. This cool, dry season is ideal for outdoor activities and provides great conditions for sightseeing.
  • Spring (March, April, May): Spring sees temperatures between 23°C and 32°C. While it can be humid, this is also when Panama experiences its blooming season, offering lush greenery and vibrant flora.
  • Summer (June, July, August): Summer temperatures can reach between 24°C and 33°C. This is the rainy season, but the showers often bring a refreshing break from the heat while making the landscapes even more vibrant.
  • Autumn (September, October, November): Autumn temperatures vary from 23°C to 32°C. This time of year features warm weather and occasional rain but is excellent for avoiding crowds and enjoying more tranquil experiences.

Frequently Asked Questions about Panama City, Panama

What is the typical cost of a cruise?

A one-week cruise to Panama City generally ranges from £1,200 to £2,800 for standard cruise lines, while luxury options may start from £2,800 to £5,500. For two-week journeys, expect to pay around £2,500 to £4,500 for regular cruises and higher for luxury experiences.

What should I expect for the costs of food and beverages?

Most meals are included onboard; however, specialty dining can range from £15 to £60 per person. Expect drink prices to range from £5 to £15 for cocktails or glasses of wine.

What are some of the dining and shopping possibilities to know about?

Onboard dining typically features various international cuisines, while Panama City is known for its vibrant street food scene and upscale restaurants. Explore local shops for handmade crafts, textiles, and unique souvenirs during your time onshore.

What are transportation options?

When docked in Panama City, many attractions are easily accessible via taxis and rideshare services. Local buses are also available, offering affordable transportation options for navigating the city.

What should I know about the local currency and making payments?

The local currency is the Balboa, but the United States Dollar (USD) is also widely accepted. Most tourist areas accept major credit and debit cards, although it’s advisable to have cash for small purchases at local markets.

What are safety and health tips to be aware of?

Panama City is generally safe for tourists, but it’s wise to stay vigilant and secure your belongings while exploring. Familiarising yourself with local health guidelines will enhance your overall experience during your visit.

What are some helpful language or cultural tips?

Spanish is the primary language spoken in Panama City, but many locals understand basic English, especially in tourist areas. Engaging respectfully with locals and embracing Panamanian customs will significantly enrich your experience.

Ready to explore the vibrant culture and stunning landscapes of Panama City, Panama? Book your cruise with Cruise1st today and embark on an unforgettable adventure in this dynamic destination!

Panama City Cruises

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Mon-Fri 9am-9pm | Sat-Sun 9am-7pm0161 938 9140